3M™ Harvest RC
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Efficient workflows. Excellent clarity.
3M™ Harvest RC Chromatographic Clarifier, BT500 is the latest addition to the 3M™ Harvest RC Chromatographic Clarifier portfolio. It's a rapid harvesting solution that saves time and steps without the need for a centrifuge.
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Speed up the discovery process with 3M™ Harvest RC Chromatographic Clarifier, BT500
The latest addition to the 3M™ Harvest RC Chromatographic Clarifier portfolio enables you to do your job in less time with less complexity. It’s an easy-to-use, bottle-top vacuum clarifier that delivers high product recoveries and DNA reduction (<500ppb*) through a streamlined workflow.
*Based on 5-8% PCV culture
Details
Highlights
- Single-stage, single-use chromatographic clarification solution
- Replaces primary, secondary, and guard membrane clarification stages
- Remove cells, cell debris and DNA (<500 ppb) from the harvested cell culture fluid
- High mAb product recovery (90-95%)
- Predictably scales from laboratory to manufacturing
- Turbidity of 3M™ Harvest RC clarified cell culture fluid <15 NTU
- Predictable scaling from discovery to manufacturing
- Lower total cost of manufacturing compared to centrifugation and depth filtration
- Lower consumption of buffer and water compared to depth filtration
- Capsules fit into laboratory to manufacturing scale workflows
3M™ Harvest RC is the next generation in harvest and clarification technology for high cell density cultures.
This solution is designed as an efficient option to increase monoclonal antibody (mAb) yields while simplifying the upstream process by replacing the centrifuge and/or depth filtration unit operations.
Suggested applications
- Clarification for CHO harvest cell culture fluid
- Single-stage chromatographic clarification
- Single-stage chromatographic clarification
Specifications
Resources
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